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Why are people still defending this crap?Post-Vaccination Syndrome: A Descriptive Analysis of Reported Symptoms and Patient Experiences After Covid-19 Immunisation https://www.medrxiv.org/content/10.1101/2023.11.09.23298266v1.full.pdfYale Listen to Immune, Symptom and Treatment Experiences Now (LISTEN) Study (online)https://medicine.yale.edu/ycci/listen-study/LISTEN study, approved by Yale University Institutional Review BoardIntroductionA chronic post-vaccination syndrome (PVS) after covid-19 vaccination has been reported but has yet to be well characterised.A chronic syndrome with symptoms that begin soon after vaccinationMethodsPeople who joined, May 2022 to July 2023N = 241 individuals, (211 from the US)aged 18 and older,who self-reported PVS after covid-19 vaccination,Deep immune profiling is used for some individualsResultsMedian age of participants, 46 yearsAmong participants with PVS127 (55%) had received BNT162b2 [Pfizer-BioNTech]86 (37%) received the mRNA-1273 [Moderna]Time from index vaccination to symptom onsetMedian time, 3 days (IQR: 1 day to 8 days). Time from vaccination to symptom survey completion595 days (IQR: 417 to 661 days)Median Euro-QoL visual analogue scale score was 50 (IQR: 39 to 70). The five most common symptomsExercise intolerance (71%)Excessive fatigue (69%)Numbness (63%)Brain fog (63%)Neuropathy (63%)In the week before survey completion(Experienced at least once in the week)Feeling unease (93%)Fearfulness (82%)Overwhelmed by worries (81%)Feelings of helplessness (80%)Anxiety (76%)Depression (76%)Hopelessness (72%)Worthlessness (49%)Concerns related to living situations and food security were also prominent. Symptom Severity When asked to quantify symptom severity on their worst days,(0 representing a trivial illness and 100 unbearable condition)Participants reported a median severity of 80Interventions to treat their conditionParticipants reported a median of 20 (IQR: 13 to 30). Oral steroids, 116 (48% participants)Gabapentin, 61 (25%)Low-dose naltrexone, 48 (20%)I, 44 (18%)Propranolol, 27 (11%)Bronchodilators, 26 (11%)More than 500 additional treatments were reported by participantsLimiting exercise or exertionQuitting alcohol or caffeineHydration and increasing salt intakeIntermittent fasting ConclusionsIn this study, individuals who reported PVS after covid-19 vaccination had low health status, high symptom burden, and high psychosocial stress,despite trying many treatments.

Bryan Turner ● 547d